Buprenorphine Treatment Outcomes among Opioid-Dependent Veterans With and Without Post-traumatic Stress Disorder

Belel Ait Oumeziane, PhD

VA Boston Healthcare System
Buprenorphine Treatment Outcomes among Opioid-Dependent Veterans With and Without Post-traumatic Stress Disorder

Scientific Abstract

Background: The opioid epidemic calls for examination and identification of the best practice in medication treatment for addiction. Buprenorphine, an opioid agonist treatment, has been shown to be a effective intervention to combat opioid addiction. We are in the process of analyzing patient and clinical variables associated with retention in buprenorphine treatment within an outpatient VA clinic in order to identify the factors that would increase successful outcome.

This outpatient clinic is located in Brockton Massachusetts and serves a diverse population of Veterans. Services include individual and group therapy, case management, psychiatry, and medication assistant therapy. The Suboxone Buprenorphine Clinic in the Alcohol Drug Treatment Program (ADTP) has been operating since 2015.

Methods: Clinical records in the ADTP outpatient clinic in the Brockton VA from 2015-2018 were reviewed and the variables of the extraction included age, gender, race, education level, employment status, service connection, marital status, combat history, MST, psychiatric diagnoses including substance use disorders, history and count of psychiatric hospitalizations, mental health care engagement, active prescriptions of buprenorphine as well as benzodiazepines and stimulants, active legal problems, and initial urine toxicology. Outcomes of interest are length in treatment and reason for treatment cessation.

The poster will include descriptive statistics of the treatment sample. Moreover, results of multiple regression and cox proportional hazards regressions across veterans with and without PTSD will be presented to determine which patient characteristics predict time in treatment and successful treatment adherence within each subsample.

Results: Data verification and analysis are in progress. Findings from the study noted above will be presented in the final poster.

Conclusions: Elucidating patient characteristics and treatment settings associated with outpatient treatment retention will better inform guidelines for prescribing opioid medications.

Live Zoom Session – April 21st

research Areas


Belel Ait Oumeziane, PhD, Justine Swanson, PsyD, Daniel Rounsaville, PhD, Grace Chang, MD, MPH